Hepatitis C Virus
Scientists at University of Heidelberg, Department of Molecular Virology publish new data on hepatitis C virus
Published in Hepatitis Weekly, June 4th, 2007
Fresh data on hepatitis C virus are presented in the report "Identification of determinants involved in initiation of hepatitis C virus RNA synthesis by using intergenotypic replicase chimeras. The 5' nontranslated region (NTR) and the X tail in the 3' NTR are the least variable parts of the hepatitis C virus (HCV) genome and play an important role in the initiation of RNA synthesis. By using subgenomic replicons of the HCV isolates Con1 (genotype 1) and JFH1 (genotype 2), we characterized the genotype specificities of the replication signals contained in the NTRs," scientists writing in the Journal of Virology report.
"The replacement of the JFH1 5' NTR and X...
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Source: Hepatitis Weekly (2007-06-04)
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