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Hepatitis C Virus Therapy

Reports from University of Barcelona advance knowledge in hepatitis C virus therapy

Published in Hepatitis Weekly, June 18th, 2007

Data detailed in "Efficacy of antiviral therapy on hepatitis C recurrence after liver transplantation: a randomized controlled study" have been presented. "Recurrence of hepatitis C virus (HCV) infection is a relevant problem of liver transplantation programs. We evaluated the effect of antiviral therapy on disease progression in 81 HCV-infected liver transplantation recipients," investigators in Barcelona, Spain report.

"Patients with mild hepatitis C recurrence (fibrosis stage F0 to F2, n=54) were randomized to no treatment (group A, n=27) or peginterferon alfa-2b/ribavirin for 48 weeks (group B, n=27). Patients with severe recurrence (F3 to F4, cholestatic hepatitis)...

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