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Hepatitis B Virus
Researchers at Peking University have published new data on hepatitis B virus
July 9th, 2007
A new study, "In vitro resistance to interferon-alpha of hepatitis B virus with basic core promoter double mutation," is now available. "The hepatitis B virus (HBV) genome basic core promoter (BCP) modulates HBeAg secretion at the transcriptional level. In addition to pre-core mutations, variations in the BCP are related to hepatitis B e antigen (HBeAg)-negative chronic hepatitis B," investigators in Beijing, People's Republic of China report. "HBeAg-negative chronic hepatitis B patients show a lower sustained response to interferon (IFN). The aim of this study was to determine if there is a relationship between HBV BCP mutation and sensitivity of HBV to IFN-alpha in...
Source: Hepatitis Weekly (2007-07-09)
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