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Hepatitis Weekly

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Hepatitis B Virus Cell Biology



Research from University of Wisconsin, Institute for Molecular Virology has provided new information about hepatitis B virus cell biology



July 9th, 2007

New research, "Involvement of host cellular multivesicular body functions in hepatitis B virus budding," is the subject of a report. "Hepatitis B virus (HBV) is a major human pathogen that chronically infects approximately 350 million people, causing liver disease and liver cancer. HBV virions bud into an endoplasmic reticulum (ER)-associated intracellular compartment, but the mechanisms of HBV assembly, budding, and release remain poorly understood," scientists in the United States report.

"Budding of retroviruses and some other enveloped RNA viruses from plasma membranes requires host functions involved in protein sorting into late endosomal multivesicular bodies...


Source: Hepatitis Weekly (2007-07-09)

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