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Hepatitis Weekly

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HIV/AIDS Therapy



Study findings from University of Cincinnati provide new insights into HIV/AIDS therapy



July 9th, 2007

New research, "Compartmentalization of hepatitis C virus (HCV) during HCV/HIV coinfection," is the subject of a report. "Extrahepatic replication has important implications for the transmission and treatment of hepatitis C virus (HCV). We analyzed longitudinal HCV diversity in peripheral-blood mononuclear cells (PBMCs) and serum during HCV monoinfection and HCV/HIV coinfection to determine whether distinct amino acid signatures characterized HCV replicating within PBMCs," scientists writing in the Journal of Infectious Diseases report.

"Analysis of E1-HVR1 sequences demonstrated higher serum genetic distances among HCV/human immunodeficiency virus...


Source: Hepatitis Weekly (2007-07-09)

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