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Hepatitis Weekly

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Alcoholism Cell Biology



Research from University College, Institute of Hepatology has provided new data on alcoholism cell biology



July 9th, 2007

Research findings, "Increased gene and protein expression of the novel eNOS regulatory protein NOSTRIN and a variant in alcoholic hepatitis," are discussed in a new report. According to a study from London, the United Kingdom, "Increased intrahepatic resistance in cirrhosis is associated with reduced endothelial NO synthase (eNOS) activity and exacerbated by superimposed inflammation. NOSTRIN induces intracellular translocation of eNOS and reduces NO generation."

"Our aims were to quantify and compare hepatic expression of eNOS, NOSTRIN, NOSIP, and caveolin-1 in alcoholic cirrhosis with or without superimposed alcoholic hepatitis and in normal livers. Biopsy specimens...


Source: Hepatitis Weekly (2007-07-09)

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