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Hepatitis C Virus

Study results from John Hunter Hospital update understanding of hepatitis c virus

Published in Hepatitis Weekly, July 30th, 2007

"Interferon (IFN) has been well documented to cause thyroid dysfunction, especially in high risk patients and when combined with ribavirin (RBV). There is very sparse data to assess if pegylated IFN will further aggravate the thyroid disease risk in comparison to regular IFN," scientists in Newcastle, Australia report.

"The purpose of this study was to assess the risk of developing, thyroid disease with pegylated IFN (pIFN) versus regular IFN (rIFN) therapy (in combination with RBV). We also pooled our results with previous studies in a meta-analysis. An observational study was made retrospectively of 24 patients who underwent a combination of rIFN and RBV therapy for,...

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