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Hepatitis Weekly

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Hepatitis B Virus Immunology



Scientists at Mie University discuss research in hepatitis B virus immunology



August 6th, 2007

Investigators publish new data in the report "Ultrastructural demonstration of hepatitis B virus production in a mouse model produced by hydrodynamic transfection." According to a study from Mie, Japan, "A mouse model of hepatitis B virus (HBV) infection produced by hydrodynamic injection of HBV DNA has been recently established. However, the ultrastructural demonstration of HBV particles in this mouse model has not as yet been reported."

"In our study, plasmid DNA containing wild-type HBV DNA was rapidly injected into 8-week-old female SCID mice via the tail vein. Serum levels of HBsAg were measured by ELISA kit. Intrahepatic HBV protein expression was detected by...


Source: Hepatitis Weekly (2007-08-06)

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