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Hepatitis Weekly

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Hepatitis B Virus Therapy



Study data from Goteborg University update understanding of hepatitis B virus therapy



August 6th, 2007

New investigation results, "Mutation analysis of lamivudine resistant hepatitis B virus strains by TaqMan PCR," are detailed in a study published in Journal of Virological Methods. According to a study from Goteborg, Sweden, "Hepatitis B virus infected patients on long-term lamivudine treatment are exposed to a 15-32% risk compounded annually of developing resistance mutations. Such resistance results in a progression of the liver damage caused by chronic hepatitis B, and may also impair the effect of other antivirals through cross-resistance."

"At present lamivudine is used frequently as monotherapy because of its relatively low price and negligible side...


Source: Hepatitis Weekly (2007-08-06)

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