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Hepatitis C Virus
Study findings from F. Pauwels et al provide new insights into hepatitis C virus
August 6th, 2007
Researchers detail in "Binding-site identification and genotypic profiling of hepatitis C virus polymerase inhibitors," new data in hepatitis C virus. "The search for hepatitis C virus polymerase inhibitors has resulted in the identification of several nonnucleoside binding pockets. The shape and nature of these binding sites differ across and even within diverse hepatitis C virus genotypes," scientists in Mechelen, Belgium report. "These differences confront antiviral drug discovery with the challenge of finding compounds that are capable of inhibition in variable binding pockets. To address this, we have established a hepatitis C virus mutant and genotypic recombinant...
Source: Hepatitis Weekly (2007-08-06)
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