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Hepatitis Weekly

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Hepatitis C Virus Therapy



Research from M.A. Thélu and co-researchers in the area of hepatitis C virus therapy published



August 6th, 2007

Scientists discuss in "IRES complexity before IFN-alpha treatment and evolution of the viral load at the early stage of treatment in peripheral blood mononuclear cells from chronic hepatitis C patients" new findings in hepatitis C virus. "At the early stage of treatment, IFN alpha-2a induces inhibition of HCV replication. The viral load reflects mainly the degradation rate of the viruses," scientists in Grenoble, France report.

"However, differences in the behavior of the viral population depend on changes, which occurred in the HCV-IRES genome. In this study, cloning and sequencing strategies permitted the generation of a large number of IRES sequences from the PBMCs...


Source: Hepatitis Weekly (2007-08-06)

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