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Hepatitis D Virus
Researchers at Graduate School target hepatitis D virus
August 6th, 2007
Research findings, "Hepatitis delta antigen binds to the clamp of RNA polymerase II and affects transcriptional fidelity," are discussed in a new report. According to recent research from Nagatsuta, Japan, "Hepatitis delta virus (HDV) is an RNA virus whose replication and transcription are considered to proceed via RNA-dependent RNA synthesis by RNA polymerase II (Pol II), and the viral protein called hepatitis delta antigen (HDAg) is essential for these processes. HDAg was previously shown to stimulate Pol II elongation on both DNA and RNA templates in vitro." "Here, the mechanism of elongation control by HDAg was investigated because it serves as a prototype of...
Source: Hepatitis Weekly (2007-08-06)
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