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Hepatitis Weekly

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Alcoholism



Findings from University of Queensland in alcoholism reported



August 6th, 2007

Fresh data on alcoholism are presented in the report "Progressive fibrosis in nonalcoholic steatohepatitis: association with altered regeneration and a ductular reaction." According to recent research from Brisbane, Australia, "Portal fibrosis and linkage is a key feature of progressive disease in nonalcoholic steatohepatitis (NASH), but not simple steatosis. It is underappreciated and poorly understood."

"Fatty liver has impaired regeneration that induces a secondary replicative pathway using bipotential, periportal, hepatic progenitor cells (HPCs). We propose that activation of this pathway, with increased cell injury in NASH, also induces a periportal ductular...


Source: Hepatitis Weekly (2007-08-06)

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