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Hepatitis Immunology
Investigators at Chinese University of Hong Kong, Institute of Digestive Disease publish new data on hepatitis immunology
August 6th, 2007
Scientists discuss in "Expression of a cyclo-oxygenase-2 transgene in murine liver causes hepatitis" new findings in hepatitis. According to a study from Shatin, Hong Kong, "It has been proved that cyclo-oxygenase-2 (COX-2) is rapidly induced by inflammatory mediators. However, it is not known whether overexpression of COX-2 in the liver is sufficient to promote activation or secretion of inflammatory factors leading to hepatitis." "To investigate the role forced expression of COX-2 in liver by using inducible COX-2 transgenic (TG) mice. TG mice that overexpress the human COX-2 gene in the liver using the liver-specific transthyretin promoter and non-TG littermates were...
Source: Hepatitis Weekly (2007-08-06)
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