Research findings, "The role of the downstream signal sequences in the maturation of the HBV middle surface glycoprotein: development of a novel therapeuticvaccine candidate," are discussed in a new report. "The signal sequences that mediate entry of the hepatitis B virus (HBV) envelope proteins into the endoplasmic reticulum (ER) are located within the S domain at positions 11-32 and at positions 80-98 (from the start of the S domain). In addition, hydrophobic patches at positions 160-184 and 189-210 of the S domain may also be involved in entry into the ER," scientists in the United States report.
"The role of each of these domains in the entry of the HBV M...
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