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Gene Therapy

Study results from Rockefeller University, Howard Hughes Medical Institute provide new insights into gene therapy

Published in Hepatitis Weekly, September 17th, 2007

Fresh data on gene therapy are presented in the report "Cellular cofactors affecting hepatitis C virus infection and replication. Recently identified hepatitis C virus (HCV) isolates that are infectious in cell culture provide a genetic system to evaluate the significance of virus-host interactions for HCV replication. We have completed a systematic RNAi screen wherein siRNAs were designed that target 62 host genes encoding proteins that physically interact with HCV RNA or proteins or belong to cellular pathways thought to modulate HCV infection," scientists in the United States report.

"This includes 10 host proteins that we identify in this study to bind HCV NS5A....

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