Hepatitis C Virus Vaccines
Findings from Wuhan University in hepatitis C virus vaccines reported
Published in Hepatitis Weekly, October 15th, 2007
Researchers detail in 'Deletion of N-glycosylation sites of hepatitis C virus envelope protein E1 enhances specific cellular and humoral immune responses,' new data in hepatitis C virus. According to recent research published in the journal Vaccine, "N-linked glycosylations of viral proteins have been implicated in immunogenicity. In this study, the effects of the N-linked glycosylation of the hepatitis C virus (HCV) E1 protein, a naturally poor immunogen, on the induction of specific immune response were examined."
"We constructed the plasmids containing the genes encoding both wild type and mutant E1 proteins in which N-linked glycosylation sites are mutated...
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Source: Hepatitis Weekly (2007-10-15)
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