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Acute Hepatitis Immunology

Reports outline acute hepatitis immunology research from Massachusetts General Hospital

Published in Hepatitis Weekly, November 5th, 2007

Researchers detail in 'Viral sequence evolution in acute hepatitis C virus infection,' new data in acute hepatitis. According to a study from the United States, "CD8(+)-T-cell responses play an important role in the containment and clearance of hepatitis C virus (HCV) infection, and an association between viral persistence and development of viral escape mutations has been postulated. While escape from CD8+ -T-cell responses has been identified as a major driving force for the evolution of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV), a broader characterization of this relationship is needed in HCV infection."

"To determine the extent,...

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