Published in Hepatitis Weekly, November 5th, 2007
"The aim of this study was to determine whether core's effects are mediated by changes in mitochondrial Ca2+ uptake. Core expression caused enhanced mitochondrial Ca2+ uptake in response to ER Ca2+ release induced by thapsigargin or ATP. It also increased mitochondrial superoxide production and mitochondrial permeability transition ( MPT). Incubating mouse liver mitochondria with an HCV core ( 100 ng/mg) in vitro increased Ca2+...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Hepatitis Weekly