Hepatitis Cell Biology
Scientists at Kyoto University report research in hepatitis cell biology
Published in Hepatitis Weekly, November 5th, 2007
New research, 'Periportal and sinusoidal liver dendritic cells suppressing T helper type 1-mediated hepatitis,' is the subject of a report. " Recently, we found that portal vein tolerance is associated with generation of Th2 cells and apoptosis of Th1 cells in the liver, which is regulated by antigen (Ag)-presenting dendritic cells (DCs) in the periportal area and sinusoids. In this study, we tested whether the periportal and sinusoidal DCs, which were loaded with an Ag in vivo, can inhibit liver injury caused by Th1 cells activated by the Ag administered systemically," investigators in Kyoto, Japan report.
"Ag-specific hepatitis model was created by adoptively...
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Source: Hepatitis Weekly (2007-11-05)
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