Combinatorial Libraries
New combinatorial libraries data have been reported by scientists at Karolinska University, Center for Molecular Medicine
Published in Hepatitis Weekly, November 19th, 2007
A new study, 'Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus,' is now available. According to recent research from Stockholm, Sweden, "One way to dissect the antibody response to an invading microorganism is to clone the antibody repertoire from immune donors and subsequently characterize the specific antibodies. Recently, methodological advances have allowed investigations of neutralizing antibodies against hepatitis C virus (HCV) in vitro."
"We have investigated three human mAbs, previously isolated from an individual infected with HCV of genotype 2b, that are known to cross-react in a binding assay to the envelope E2...
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Source: Hepatitis Weekly (2007-11-19)
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