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Hepatitis B Virus

New hepatitis B virus study findings have been reported from C.M. Olinger et al

Published in Hepatitis Weekly, November 19th, 2007

According to a study from Junglinster, Luxembourg, "The major neutralizing epitope, the ''a'' determinant of the hepatitis B virus (HBV) genotype E surface antigen (HBsAg) is most divergent from that of genotype A, which is used for preparing monoclonal antibodies used in commercially available HBV reagents. To evaluate the performance of the latest generation of HBsAg detection assays with respect to genotype E HBsAg."

"Three commercial assays were evaluated using sera from 200 Nigerian patients compared to the preS/S sequence of DNA positive samples. Out of 200 samples, 61 and 103 gave concordant positive and negative results between the three HBsAg assays. Of 36...

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