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Hepatitis C Virus

New hepatitis C virus findings from A. Arasappan and co-authors described

Published in Hepatitis Weekly, November 19th, 2007

According to a study from the United States, "A practical and efficient route toward synthesis of amino acid derivatives containing P-quaternary center has been developed using diastereo selective Strecker reaction."

"The method was employed for preparation of > 100 g of P-methylcyclohexyl glycine derivative, 21," wrote A. Arasappan and colleagues.

The researchers concluded: "Incorporation of some of the hindered amino acid derivatives at the P3 position resulted in potent HCV NS3 serine protease inhibitors."

Arasappan and colleagues published their study in Tetrahedron Letters (Practical and efficient method for amino...

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