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Hepatitis C Virus Therapy

Study findings from Erasmus University broaden understanding of hepatitis C virus therapy

Published in Hepatitis Weekly, November 26th, 2007

Scientists discuss in 'Gamma-glutamyltransferase and rapid virological response as predictors of successful treatment with experimental or standard peginterferon-alpha-2b in chronic hepatitis C non-responders' new findings in hepatitis C virus. "High-dose peginterferon-alpha (PegIFN-alpha) induction and prolongation of therapy may be an option to improve sustained virological response (SVR) rates among hepatitis C virus (HCV) non-responders, although a higher and a longer dosing of PegIFN-alpha may intensify side effects We randomized 53 patients, who previously failed with standard IFN-alpha±ribavirin, to a high-dose induction and an extended regimen with PegIFN-alpha-2b [3.0...

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