Hepatitis B Virus Genetics
Research data from Baylor College of Medicine, Department of Medicine update understanding of hepatitis B virus genetics
Published in Hepatitis Weekly, December 3rd, 2007
Researchers detail in 'Hepatitis B virus genetic diversity and its impact on diagnostic assays,' new data in hepatitis B virus. According to recent research from the United States, "Hepatitis B virus (HBV) circulates in blood as closely related, but genetically diverse molecules called quasispecies. During replication, HBV production may approach 10(11) molecules/day, although during peak activity this rate may increase 100-1000 times."
"Generally, DNA polymerases have excellent fidelity in reading DNA templates because they are associated with an exonuclease which removes incorrectly added nucleotides. However, the HBV-DNA polymerase lacks fidelity and proofreading...
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Source: Hepatitis Weekly (2007-12-03)
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