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Hepatitis B Virus Gene Therapy

Reports on hepatitis B virus gene therapy findings from Southern Medical University, Department of Radiation Medicine provide new insights

Published in Hepatitis Weekly, December 17th, 2007

Research findings, 'Downregulation of HBx mRNA in HepG2.2.15 cells by small interfering RNA,' are discussed in a new report. According to recent research from Guangzhou, People's Republic of China, "Hepatitis B virus (HBV) infection is one of the most prevalent viral infectious diseases in humans. And it is still a challenge for the development of an effective therapy for HBV infection."

"Recently, the progress in RNA interference (RNAi) has shed some light on the inhibition of HBV expression and replication by RNAi specific for the various genes of the HBV genome. Some prior researches suggests that the HBV x protein (HBx) plays an important role in viral...

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