Hepatitis A Virus

New findings reported from Northwestern University describe advances in hepatitis A virus

Published in Hepatitis Weekly, January 7th, 2008

According to a study from the United States, "Cadherin-mediated interactions are integral to synapse formation and potentiation. Here we show that N-cadherin is required for memory formation and regulation of a subset of underlying biochemical processes."

"N-cadherin antagonistic peptide containing the His-Ala-Val motif (HAV-N) transiently disrupted hippocampal N-cadherin dimerization and impaired the formation of long-term contextual fear memory while sparing short-term memory, retrieval, and extinction. HAV-N impaired the learning-induced phosphorylation of a distinctive, cytoskeletally associated fraction of hippocampal Erk-1/2 and altered the distribution of IQGAP1,...

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Source: Hepatitis Weekly (2008-01-07)

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