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Hepatitis B Virus

Studies conducted at W. Sun et al on hepatitis B virus recently published

Published in Hepatitis Weekly, January 21st, 2008

According to recent research from Beijing, People's Republic of China, "Hepatocellular carcinoma (HCC) is a highly malignant tumor, and chronic infection with hepatitis B virus is one of its major risk factors. To identify the proteins involved in HCC carcinogenesis, we used two-dimensional fluorescence DIGE to study the differentially expressed proteins in tumor and adjacent nontumor tissue samples."

"Samples from 12 hepatitis B virus-associated HCC patients were analyzed. A total of 61 spots were significantly up-regulated ( ratio >= 2, p<= 0.01) in tumor samples, whereas 158 spots were down-regulated ( ratio <= -2, p<= 0.01). Seventy-one gene products...

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