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Hepatitis B Virus

Research results from Chinese University of Hong Kong update knowledge of hepatitis B virus

Published in Hepatitis Weekly, February 11th, 2008

"The efficacy of nucleoside and nucleotide analogues for hepatitis B has been linked to the magnitude and durability of hepatitis B virus (HBV) suppression. To compare the antiviral efficacy of telbivudine and adefovir dipivoxil, and the effects of switching from adefovir to telbivudine, in hepatitis B e antigen (HBeAg)-positive patients with chronic hepatitis B. Randomized, controlled, open-label trial," scientists in Hong Kong, People's Republic of China report.

"16 outpatient clinics. 135 treatment-naive, HBeAg-positive adults with chronic hepatitis B. Patients were randomly assigned in a 1: 1:1 ratio to 52 weeks of telbivudine (group A) or adefovir (group B), or...

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