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HIV/AIDS

Study data from L. Castera and co-authors update knowledge of HIV/AIDS

Published in Hepatitis Weekly, February 25th, 2008

"[LEAD] Significance of steatosis in HIV-HCV coinfection remains controversial. [LEAD] To compare the prevalence and predictors of hepatic steatosis between HIV-HCV and HCV patients matched for steatosis known determinants," scientists in Pessac, France report.

"[MATERIALSXXXMETHODS] A total of 564 HCV-naive patients undergoing liver biopsy were studied: 137 with HIV-HCV coinfection and 427 with HCV monoinfection, among whom 137 were matched for age, gender, body mass index and HCV genotype. [RESULTS] Steatosis of any grade (67.1% vs. 41.6%, P< 0.0001), mixed steatosis ( 55.4% vs. 21.1%, P< 0.0001), severe histological activity (A2-A3: 78.1% vs. 55.5%, P<...

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