Liver Transplant

Researchers from Kyushu University detail new studies and findings in the area of liver transplant

Published in Hepatitis Weekly, February 25th, 2008

According to a study from Fukuoka, Japan, "The optimal management in living donor liver transplantation using an ABO incompatible donor with a high isoagglutinin titer is still uncertain. Our patient was a 20-year-old woman with fulminant hepatitis."

"The only available donor was her 54-year-old father-in-law of an incompatible blood type. The initial isoagglutinin titer was 2048X. She received 375 mg/m(2) of anti-CD20 antibody 3 days before the living donor liver transplantation with concomitant splenectomy. Despite daily plasma exchanges after transplantation, the isoagglutinin titer started to shoot up to its maximum value of 2048X, with a sudden decline in the bile...

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Source: Hepatitis Weekly (2008-02-25)

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