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Hepatitis C Virus

Perlegen and SC Liver Research Consortium to Collaborate on Interferon Response in Hepatitis C Patients

Published in Hepatitis Weekly, March 3rd, 2008

Perlegen Sciences, Inc., and the SC Liver Research Consortium (SCLRC), announced a collaboration to discover genetic variations that predict which patients with hepatitis C (HCV) are most likely to benefit from treatment. The parties will conduct large scale genetic studies on samples from hundreds of patients with HCV who have been treated, successfully and unsuccessfully, with interferon alfa and ribavirin, the current standard of care for this disease.

The cure rate for HCV patients treated with interferon alfa and ribavirin is roughly 50%. Unfortunately, irrespective of efficacy, the treatment results in serious side effects including flu-like symptoms, fatigue,...

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