Hepatitis Immunology
New hepatitis immunology study findings reported from University of Ulsan, Department of Gastroenterology
Published in Hepatitis Weekly, March 10th, 2008
Fresh data on hepatitis are presented in the report 'Susceptibility to type 1 autoimmune hepatitis is associated with shared amino acid sequences at positions 70-74 of the HLA-DRB1 molecule.' According to recent research published in the Journal of Hepatology, "The risk of developing autoimmune hepatitis (AIH) has been suggested to be associated with the presence of HLA-DRB1 alleles encoding the 'shared epitope' at amino acid positions 67-72 in the third hypervariable region (HVR3) of DRbeta. We aimed to identify the specific HLA alleles that are susceptible to type 1 AIH in Koreans, and to validate the shared epitope hypothesis in this single ethnic group."
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Source: Hepatitis Weekly (2008-03-10)
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