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Hepatitis C Virus Genetics

Study data from National Institute of Infectious Disease, Infectious Diseases Department update knowledge of hepatitis C virus genetics

Published in Hepatitis Weekly, May 5th, 2008

New research, 'Dynamic behavior of hepatitis C virus quasispecies in a long-term culture of the three-dimensional radial-flow bioreactor system,' is the subject of a report. "Hepatitis C virus (HCV) exists in infected individuals as quasispecies, usually consisting of a dominant viral isolate and a variable mixture of related, yet genetically distinct, variants. A prior HCV infection system was developed using human hepatocellular carcinoma cells cultured in the three-dimensional radial-flow bioreactor (RFB), in which the cells retain morphological appearance and their differentiated hepatocyte functions for an extended period of time," scientists in Tokyo, Japan report.

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