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Hepatitis B Virus

Research conducted at Chang-Gung University has provided new information about hepatitis B virus

Published in Hepatitis Weekly, May 26th, 2008

According to a study from Taipei, Taiwan, "Background/aims Chronic hepatitis B and hepatitis C are common causes of liver fibrosis and cirrhosis. We performed a comparative study on the expression of alpha-smooth muscle actin (alpha-SMA) in hepatic stellate cells (HSCs), a marker of HSC activation, in patients with chronic hepatitis B and hepatitis C. Patients and methods Using immunohistochemistry and a semi-quantitative scoring method, the expression of alpha-SMA in HSCs was studied in patients with chronic hepatitis B (n = 50) and hepatitis C (n = 50)."

"The HSC activation index was correlated with age, sex, AST, ALT, viral genotype, viral titers, degrees of hepatic...

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