Hepatitis B Virus

Study results from Johns Hopkins University, Medical Department provide new insights into hepatitis B virus

Published in Hepatitis Weekly, May 26th, 2008

According to a study from the United States, "Occult infection with hepatitis B virus (HBV) is a type of chronic HBV infection that is characterized by the absence of a detectable hepatitis B surface antigen in the blood and by very low levels of HBV DNA in the blood and liver. The mechanisms leading to occult HBV infection remain poorly understood but include possible genetic mutations and deletions."

"Recently, it has been shown that HBV has CpG islands that are methylated, raising the possibility that epigenetic changes may also be important. The full-length genomes of isolates from 5 cases of occult HBV infection were cloned and analyzed for mutations and deletions....

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Source: Hepatitis Weekly (2008-05-26)

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