Hepatitis C Virus

University of Pennsylvania reports research in hepatitis C virus

Published in Hepatitis Weekly, August 11th, 2008

According to recent research published in the journal Hepatology, "The outcome of hepatitis C virus (HCV) infection has been associated with antiviral CD4 T cell response, human leukocyte antigens (HLA) class II genotypes, and ethnicity. However, HLA class II molecules restrict the nature of CD4 T cell response, and HLA distributions differ between ethnic groups."

"In this study, we asked whether HLA class II genotypes associated with HCV clearance are shared between Caucasian and African Americans and whether they contribute to enhanced antiviral CD4 T cell response. In a cohort of 93 HCV-seropositive subjects from Northeast America with defined ethnicity,...

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Source: Hepatitis Weekly (2008-08-11)

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