HIV/AIDS
Researchers from University of Frankfurt report details of new studies and findings in the area of HIV/AIDS
Published in Hepatitis Weekly, September 29th, 2008
"Pharmacokinetic differences, contributing to drug-related side effects, between men and women have been reported for HIV protease inhibitors. As only limited and inconclusive data on ritonavir-boosted atazanavir are available, we evaluated the respective steady-state pharmacokinetics in 48 male and 26 female HIV-1-infected adults receiving atazanavir/ritonavir 300/100 mg once-daily as part of their antiretroviral therapy," investigators in Frankfurt, Germany report.
"Pharmacokinetic profiles (24 h) of atazanavir/ritonavir were assessed and measured by HPLC/tandem mass spectrometry. Geometric mean (GM; ANOVA) of minimum and maximum plasma drug concentrations (C-min and...
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Source: Hepatitis Weekly (2008-09-29)
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