Hepatitis

New hepatitis research reported from Chiba University

Published in Hepatitis Weekly, September 29th, 2008

According to a study from Matsudo, Japan, "D-Galactosamine (GaIN) induces acute hepatitis in experimental animals and this hepatitis has been shown to be suppressed by preceding ingestion of amino acids such as Gly, L-Ser, and L-GIn. However, little is known about the mechanism of its action."

"The present study shows for the first time that IL-18 reduction is involved in the suppressive actions Of L-GIn and L-Ser on GaIN-induced hepatitis. Elevation of IL-18 mRNA expression in liver and its concentration in serum in GaIN-treated rats were found to be suppressed by preceding ingestion of 10% L-Gln- or 10% L-Ser diets, and resulted in the attenuation of the increase in...

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Source: Hepatitis Weekly (2008-09-29)

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