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Hepatitis C Virus Therapy

Research in the area of hepatitis C virus therapy reported from Okayama University

Published in Hepatitis Weekly, October 20th, 2008

New investigation results, 'A new living cell-based assay system for monitoring genome-length hepatitis C virus RNA replication,' are detailed in a study published in Virus Research. "We previously developed a cell-based luciferase reporter assay system for monitoring genome-length hepatitis C virus (HCV) RNA replication (OR6 assay system). Here, we aimed to develop a new living cell-based reporter assay system using enhanced green fluorescent protein (EGFP)," scientists writing in the journal Virus Research report.

"Genome-length HCV RNAs encoding EGFP were introduced into a subline of HuH-7 cells and G418 selection was performed. One cloned cell line,...

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