Life Sciences

New life sciences data have been reported by researchers at University of Sherbrooke

Published in Hepatitis Weekly, October 27th, 2008

"The transcription factor Pax-5, is vital during B lymphocyte differentiation and is known to contribute to the oncogenesis of certain cancers. The Pax-5 locus generates multiple yet structurally related mRNA transcripts through the specific activation of alternative promoter regions and/or alternative splicing events which poses challenges in the study of specific isoform function," scientists in Sherbrooke, Canada report.

"In this study, we investigated the function of a major Pax-5 transcript, Pax-5B using an enhanced version of the Hepatitis Delta Virus ribozyme (HDV Rz) suppression system that is specifically designed to recognize and cleave the human Pax-5B mRNA....

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Source: Hepatitis Weekly (2008-10-27)

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