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Hepatitis C Virus
Researchers at Chiba Institute of Technology publish new data on hepatitis C virus
October 27th, 2008
A new study, 'Suppression of hepatitis C virus replication by baculovirus vector-mediated short-hairpin RNA expression,' is now available. According to recent research published in the journal FEBS Letters, "Short-hairpin RNAs (shRNAs) inhibit gene expression by RNA interference." "Here, we report on the inhibition, by baculovirus-based vector-derived shRNAs, of core-protein expression in full-length hepatitis C virus (HCV) replicon cells. shRNAs were designed to target the highly conserved core region of the HCV genome. In particular, the core-shRNA452 containing nucleotides 452-472, as the target in the HCV core gene, dramatically inhibited the expression of...
Source: Hepatitis Weekly (2008-10-27)
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