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Hepatitis B Virus

Reports by S.H. Kim and co-researchers describe recent advances in hepatitis B virus

Published in Hepatitis Weekly, October 27th, 2008

"The virus neutralizing efficacy of HB-C7A, a human monoclonal antibody raised against the surface antigen of hepatitis B virus (HBsAg), was proved using hepatitis B virus (HBV)-naive chimpanzees. One control chimpanzee which received 100 CID50 of HBV, subtype adw, without HB-C7A antibody became infected by HBV as evidenced by the appearance of HBV DNA on week 10 and subsequent appearance of HBsAg, anti-HBc and anti-HBs in the serum," scientists in South Korea report.

"Two experimental chimpanzees were inoculated intravenously with same dose of HBV as the control chimpanzee, which was previously incubated with 0.1 mg and 10 mg of HB-C7A antibody prior to inoculation....

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