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Hepatitis C Virus

New findings reported from University of Heidelberg, Department of Molecular Virology describe advances in hepatitis C virus

Published in Hepatitis Weekly, November 10th, 2008

Scientists discuss in 'Structural and functional characterization of nonstructural protein 2 for its role in hepatitis C virus assembly' new findings in hepatitis C virus. "The hepatitis C virus (HCV) is a flavivirus replicating in the cytoplasm of infected cells. The HCV genome is a single-stranded RNA encoding a polyprotein that is cleaved by cellular and viral proteases into 10 different products," scientists in Heidelberg, Germany report.

"While the structural proteins core protein, envelope protein 1 (E1) and E2 build up the virus particle, most nonstructural (NS) proteins are required for RNA replication. One of the least studied proteins is NS2, which is composed...

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