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Hepatitis C Virus

Scientists at University of North Carolina release new data on hepatitis C virus

Published in Hepatitis Weekly, November 17th, 2008

According to a study from the United States, "Treatment response remains suboptimal for many patients with chronic hepatitis C, particularly those with genotype 1 and high levels of viremia. The efficacy of high-dose regimens of peginterferon alfa-2a and ribavirin was compared with conventional dose regimens in patients with features predicting poor treatment responses."

"Eligible treatment-naive adults with genotype I infection, hepatitis C virus (HCV) RNA >800,000 IU/mL and body weight >85 kg were randomized to double-blind treatment with peginterferon alfa-2a at 1.80 or 270 mu g/week plus ribavirin at 1200 or 1600 mg/day for 48 weeks (four regimens were...

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