Hepatitis
Research results from Y. Igarashi and colleagues update understanding of hepatitis
Published in Hepatitis Weekly, December 1st, 2008
"Previously., we created, a chimeric mouse (humanized mouse), a severe combined immunodeficiency (SCID) mouse whose liver was > 90% repopulated with human (h)-hepatocytes., which are useful for the testing of drug metabolism and toxicity. as well as a hepatitis B virus and hepatitis C Virus-susceptible animal model. However, their small body size and small total blood Volume limited the utilization for analytical purposes, which led us to develop a method to create a chimeric rat bearing h-hepatocyte-repopulated liver," scientists writing in the journal Xenotransplantation report.
"F344 nude rats devoid of T cells were irradiated with X-rays and injected with...
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Source: Hepatitis Weekly (2008-12-01)
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