Alcoholism
Study results from S. Nakano and colleagues in the area of alcoholism published
Published in Hepatitis Weekly, December 8th, 2008
According to a study from Nagano, Japan, "The aim of this study was to investigate the preventive actions of bezafibrate against non-alcoholic steatohepatitis (NASH), the activation of hepatic stellate cells (HSC), and fibrogenesis by using a model of NASH and an in vitro model. Male KK-A(y)/TaJcl (KK-A(y)) mice were fed a methionine and choline-deficient (MCD) diet or a MCD diet containing bezafibrate or pioglitazone for 7 weeks, after which biochemical parameters, pathological changes, and hepatic mRNA levels were assessed."
"An in vitro HSC model was designed by using a previously described RI-T cell line stimulated by transforming growth factor-beta 1 (TGF-beta 1)....
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Source: Hepatitis Weekly (2008-12-08)
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