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Hepatitis C Virus

Reports from University of Frankfurt add new data to research in hepatitis C virus

Published in Hepatitis Weekly, December 22nd, 2008

"The impact of amantadine on virologic response rates of interferon-based treatment of chronic hepatitis C is controversial. The aim of this study was to compare virological response rates in patients with chronic hepatitis C virus (HCV)-1 infection treated with 400 mg amantadine or placebo in combination with peginterferon alfa-2a (40 kD) and ribavirin for 48 weeks," investigators in Frankfurt, Germany report.

"Seven hundred four previously untreated chronically HCV-1-infected patients (mean age, 46 +/- 12 years) were randomized to (A) amantadine-sulphate (400 mg/day) (n = 352) or (B) placebo (n = 352), both in combination with 180 jig peginterferon alfa-2a once weekly...

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