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Hepatitis C Virus

Research conducted at Kobe University has provided new information about hepatitis C virus

Published in Hepatitis Weekly, December 22nd, 2008

According to recent research published in the Journal of Virology, "We previously reported that cells harboring the hepatitis C virus (HCV) RNA replicon as well as those expressing HCV NS3/4A exhibited increased sensitivity to suboptimal doses of apoptotic stimuli to undergo mitochondrion-mediated apoptosis (Y. Nomura-Takigawa, et al., J. Gen. Virol. 87: 1935-1945, 2006)."

"Little is known, however, about whether or not HCV infection induces apoptosis of the virus-infected cells. In this study, by using the chimeric J6/JFH1 strain of HCV genotype 2a,we demonstrated that HCV infection induced cell death in Huh7.5 cells. The cell death was associated with...

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