Hepatitis A Virus
Researchers from University of Texas detail new studies and findings in the area of hepatitis A virus
Published in Hepatitis Weekly, December 22nd, 2008
According to recent research published in the Journal of Virology, "Internally located, cis-acting RNA replication elements (cre) have been identified within the genomes of viruses representing each of the major picornavirus genera (Enterovirus, Rhinovirus, Aphthovirus, and Cardiovirus) except Hepatovirus. Previous efforts to identify a stem-loop structure with cre function in hepatitis A virus (HAV),the type species of this genus, by phylogenetic analyses or thermodynamic predictions have not succeeded."
"However, a region of markedly suppressed synonymous codon variability was identified in alignments of HAV sequences near the 5' end of the 3D(pol)-coding...
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Source: Hepatitis Weekly (2008-12-22)
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